We discover new enzymes for your reaction or process. With our point-cloud technology we find suitable candidates based on the properties of active sites. Our CatalophoreTM platform gives you the opportunity to perform the following tasks:
novel biochemical reactions (e.g., proteins with altered substrate specificity and selectivity)
engineering/optimization of existing protein properties (e.g., activity, stability, robustness),
extension of freedom to operate (FTO) by identifying and developing alternative proteins, or - the acceleration and improvement of improving established optimization strategies employing engineering
acceleration and improvement of existing engineering optimization strategies
Additional bioinformatics services: homology modeling (automated modeling for large datasets is also available), substrate docking (single or automated docking using our cavity-guided docking approach), or molecular-dynamics (MD) simulations
Case Study
Here comes a text about enzyme discovery (maybe Phytase) that shortly outlines what the project is about and what the desired outcome should be. This text also hints in which industry the customer works without naming the customer directly.
Classical approach
Sample size
1500
TEsted in the Lab
500
Improvement
1.5-fold
Time spend
30 weeks
Innophore approach
Sample size
15.000.000
TEsted in the Lab
20
Improvement
20-fold
Time spend
3 weeks
Follow-up wet-lab projects and work packages
Upon request, our cooperation partners can provide you with biochemical expertise for follow-up wet-lab projects and work packages.
New ways to search
We discover new enzymes for your reaction or process. With our point-cloud technology we find suitable candidates based on the properties of active sites. Our CatalophoreTM platform gives you the opportunity to perform the following tasks:
novel biochemical reactions (e.g., proteins with altered substrate specificity and selectivity)
engineering/optimization of existing protein properties (e.g., activity, stability, robustness),
extension of freedom to operate (FTO) by identifying and developing alternative proteins, or - the acceleration and improvement of improving established optimization strategies employing engineering
acceleration and improvement of existing engineering optimization strategies
Additional bioinformatics services: homology modeling (automated modeling for large datasets is also available), substrate docking (single or automated docking using our cavity-guided docking approach), or molecular-dynamics (MD) simulations
Follow-up wet-lab projects and work packages
Upon request, our cooperation partners can provide you with biochemical expertise for follow-up wet-lab projects and work packages.
Case study
Back in 2014, we demonstrated the power of 3D point clouds in enzyme search. Instead of sequence searches, finding a similar cavity led to a surprising result.
Even though our platforms are ready-to-use, we do not believe in one-fits-all solutions. Tailor-made software solutions help you optimize your R&D pipeline and redefine how you solve problems. Our developers are committed to eliminating bottlenecks and adapting our CatalophoreTM platform to your needs. Our AI-driven technologies learn and grow with your projects and are customizable to your goals.