Protein-protein-interactions and drug discovery
In-silico drug repurposing studies are a fast and efficient way to screen for new drug candidates to combat new or rare diseases. With our point-cloud-technology we provide in-sillico support in the following fields:
- Drug discovery for traget binding sites (small molecule binding)
- Protein-Protein-interaction screening with our Catalophore Halo technology
- In-silico Drug repurposing screening
- Site effect prediction
- Optimization of existing workflows (lowering time, cost, false-positive rate etc.)
Follow-up wet-lab projects and work packages
Upon request, our cooperation partners can provide you with biochemical expertise for follow-up wet-lab projects and work packages.
Case study
Since the onset of the COVID-19 pandemic, we have been able to help shed more light on the nature of the SARS-CoV-2 virus through a series of studies.
Read more here.
In a recent structural bioinformatics approach, we gained new insights into the impact of amino acid exchanges on the affinity of the spike RBD for the human receptor hACE2.
Read more here: Structural bioinformatics analysis of SARS-CoV-2 variants reveals higher hACE2 receptor binding affinity for Omicron B.1.1.529 spike RBD compared to wild type reference
Durmaz, V., Köchl, K., Krassnigg, A. et al., Sci Rep 12, 14534 (2022).
Special problems require special solutions
Even though our platforms are ready-to-use, we do not believe in one-fits-all solutions. Tailor-made software solutions help you optimize your R&D pipeline and redefine how you solve problems. Our developers are committed to eliminating bottlenecks and adapting our CatalophoreTM platform to your needs. Our AI-driven technologies learn and grow with your projects and are customizable to your goals.
