The discovery engine for the molecular world.
We map every protein binding site as a searchable hyperdimensional point-cloud fingerprint, so you can find enzymes, drugs and off-targets by what they do, not how they look. The method the press called the Google for enzymes.
Proteins matter, but binding sites matter even more.
Catalophore describes every protein cavity as a multidimensional point cloud, which lets us search across whole proteomes by the shape and chemistry of an active site. That single idea drives enzyme discovery, drug repurposing, off-target safety screening and protein engineering, all on the same technology.
One technology, three ways to use it.
Bring a reaction, a target, a sequence or a process question. Pick the path that fits how you work.
Discovery as a service
We run computational discovery and engineering for you on the same technology. You keep the IP on every enzyme, hit and variant we deliver.
Explore the services →Tools for your team
A full on-premise platform, a desktop cavity workbench, a cloud copilot for off-target search and a plugin for PyMOL. Pick the one that fits your workflow.
Explore the software →Catalophore science
The point-cloud cavity engine behind everything we do, with applied solutions for pharma and biotechnology and a decade of peer-reviewed publications.
Explore the technology →Cavity science, applied to your industry.
We run computational discovery and engineering as a service, on the same technology behind our software. Bring a reaction, a target or a sequence and we come back with a scoped proposal and an honest call on feasibility.
for Biotechnology Industrial enzymes built for your process: thermostability, pH range, selectivity or activity on a non-native substrate.
for Pharma Hit identification, drug repurposing, proteome-wide off-target screening and biocatalysis, binding site first.
One technology. Four ways to put it to work.
Every Innophore tool runs on the same Catalophore point-cloud cavity technology. From a full platform behind your firewall to a plugin for the viewer you already use.
The full platform, on your own site.
Every structure, sequence, cavity, ligand and experiment in one workbench, on your own data and compute, behind your firewall.
The protein cavity workbench.
Turn a raw structure into an interpreted binding site in seconds: point-cloud detection, property fields, docking and proteome-wide search.
The cloud copilot for off-target search.
AI-assisted off-target search built on the human cavitome. Submit a binding site, get a ranked list with the structural evidence behind every match.
Cavity analysis inside PyMOL.
Bring Catalophore cavity detection and CavitOmiX matching straight into the viewer you already use, without switching tools.
From a structure to a searchable hyperdimensional point-cloud fingerprint.
Catalophore treats a binding site as a 3D point cloud carrying shape and physico-chemical properties, then searches across entire proteomes for cavities that match, well beyond what sequence or fold comparison can show. The same core idea behind our Nature Communications paper a decade ago, now run at proteome scale on GPUs.
Published since 2014 and validated with global pharma, NVIDIA, AWS and Google, with their scientists co-authoring the peer-reviewed work.
Read the publications →
A decade of cavity science, run at proteome scale.
Bring us a problem.
Send a reaction, a target, a sequence or a process question. We come back with a scoped proposal and an honest call on feasibility.